Mitochondrial Akt-regulated mitochondrial apoptosis signaling in cardiac muscle cells
نویسندگان
چکیده
منابع مشابه
Mitochondrial Akt-regulated mitochondrial apoptosis signaling in cardiac muscle cells.
We recently reported translocation and activation of Akt in cardiac mitochondria. This study was to determine whether activation of Akt in mitochondria could inhibit apoptosis of cardiac muscle cells. Insulin stimulation induced translocation of phosphorylated Akt to the mitochondria in primary cardiomyocytes. A mitochondria-targeted constitutively active Akt was overexpressed via adenoviral ve...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2012
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.00455.2011